What is LODLoss on drying (LOD) is a test used to determine the moisture content of a sample by measuring the weight loss after drying. It is typically used in the pharmaceutical, food, and chemical industries to ensure that products meet specifications for moisture content. The test involves drying a sample at a specific temperature and time, and then weighing the sample before and after to determine the weight loss, which is expressed as a percentage of the original weight. The LOD test can be done using various techniques, such as oven drying, infrared drying or vacuum drying.